Management of liver metastases from gastric carcinoma: where is the evidence?
Identifieur interne : 000189 ( Main/Exploration ); précédent : 000188; suivant : 000190Management of liver metastases from gastric carcinoma: where is the evidence?
Auteurs : Hichem Jerraya ; Ahmed Saidani ; Mehdi Khalfallah ; Ibtissem Bouasker ; Ramzi Nouira ; Chedly DziriSource :
- La Tunisie medicale [ 0041-4131 ] ; 2013.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Tumeurs de l'estomac.
- secondaire : Tumeurs du foie.
- thérapie : Tumeurs du foie.
- Humains.
English descriptors
- KwdEn :
- MESH :
- pathology : Stomach Neoplasms.
- secondary : Liver Neoplasms.
- therapy : Liver Neoplasms.
- Humans.
Abstract
BACKGROUND
Liver metastases of gastric carcinoma are often the synonym of advanced neoplastic disease which has long justified the indication of palliative chemotherapy. However, inspired by the good results of the management of liver metastases of colorectal cancers,several surgeons have focused on the treatment of liver metastases of gastric carcinoma. The different therapeutic modalities used are surgery, radiofrequency ablation, hepatic arterial infusion and palliative gastrectomy.
AIMS
To provide evidence based answer to the following questions regarding liver metastases from gastric carcinoma: 1. What is the indication of surgery? 2. Does radiofrequency ablation useful? 3. What is the contribution of the hepatic arterial infusion? 4. Is there any benefit to palliative gastrectomy?
METHODS
A literature search on PubMed database over the period from January 1990 to December 2011 was conducted using as key words "gastric cancer" and "liver metastases".
RESULTS
Surgery of a single liver metastasis smaller than 5 cm and not associated with another metastatic site offers better results in terms of 5-year survival rate than palliative chemotherapy. Intra hepatic arterial chemotherapy offers an alternative to surgery in inoperable patients and can be proposed as neo adjuvant treatment to surgery. The interest of radiofrequency ablation and palliative gastrectomy remains unproven.
CONCLUSION
Surgery is a good indication for single liver metastasis of gastric carcinoma less than 5 cm and not associated with another extra hepatic metastasis.
PubMed: 23404586
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000631
- to stream PubMed, to step Curation: 000627
- to stream PubMed, to step Checkpoint: 000615
- to stream Main, to step Merge: 000189
- to stream Main, to step Curation: 000189
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Management of liver metastases from gastric carcinoma: where is the evidence?</title><author><name sortKey="Jerraya, Hichem" sort="Jerraya, Hichem" uniqKey="Jerraya H" first="Hichem" last="Jerraya">Hichem Jerraya</name><affiliation><nlm:affiliation>Department "B" of General Surgery, Charles Nicolle's Hospital, Tunis El Manar University, Faculty of Medicine of Tunis.</nlm:affiliation><wicri:noCountry code="subField">Faculty of Medicine of Tunis</wicri:noCountry></affiliation></author><author><name sortKey="Saidani, Ahmed" sort="Saidani, Ahmed" uniqKey="Saidani A" first="Ahmed" last="Saidani">Ahmed Saidani</name></author><author><name sortKey="Khalfallah, Mehdi" sort="Khalfallah, Mehdi" uniqKey="Khalfallah M" first="Mehdi" last="Khalfallah">Mehdi Khalfallah</name></author><author><name sortKey="Bouasker, Ibtissem" sort="Bouasker, Ibtissem" uniqKey="Bouasker I" first="Ibtissem" last="Bouasker">Ibtissem Bouasker</name></author><author><name sortKey="Nouira, Ramzi" sort="Nouira, Ramzi" uniqKey="Nouira R" first="Ramzi" last="Nouira">Ramzi Nouira</name></author><author><name sortKey="Dziri, Chedly" sort="Dziri, Chedly" uniqKey="Dziri C" first="Chedly" last="Dziri">Chedly Dziri</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2013">2013</date><idno type="RBID">pubmed:23404586</idno><idno type="pmid">23404586</idno><idno type="wicri:Area/PubMed/Corpus">000631</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000631</idno><idno type="wicri:Area/PubMed/Curation">000627</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000627</idno><idno type="wicri:Area/PubMed/Checkpoint">000615</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000615</idno><idno type="wicri:Area/Main/Merge">000189</idno><idno type="wicri:Area/Main/Curation">000189</idno><idno type="wicri:Area/Main/Exploration">000189</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Management of liver metastases from gastric carcinoma: where is the evidence?</title><author><name sortKey="Jerraya, Hichem" sort="Jerraya, Hichem" uniqKey="Jerraya H" first="Hichem" last="Jerraya">Hichem Jerraya</name><affiliation><nlm:affiliation>Department "B" of General Surgery, Charles Nicolle's Hospital, Tunis El Manar University, Faculty of Medicine of Tunis.</nlm:affiliation><wicri:noCountry code="subField">Faculty of Medicine of Tunis</wicri:noCountry></affiliation></author><author><name sortKey="Saidani, Ahmed" sort="Saidani, Ahmed" uniqKey="Saidani A" first="Ahmed" last="Saidani">Ahmed Saidani</name></author><author><name sortKey="Khalfallah, Mehdi" sort="Khalfallah, Mehdi" uniqKey="Khalfallah M" first="Mehdi" last="Khalfallah">Mehdi Khalfallah</name></author><author><name sortKey="Bouasker, Ibtissem" sort="Bouasker, Ibtissem" uniqKey="Bouasker I" first="Ibtissem" last="Bouasker">Ibtissem Bouasker</name></author><author><name sortKey="Nouira, Ramzi" sort="Nouira, Ramzi" uniqKey="Nouira R" first="Ramzi" last="Nouira">Ramzi Nouira</name></author><author><name sortKey="Dziri, Chedly" sort="Dziri, Chedly" uniqKey="Dziri C" first="Chedly" last="Dziri">Chedly Dziri</name></author></analytic><series><title level="j">La Tunisie medicale</title><idno type="ISSN">0041-4131</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Humans (MeSH)</term><term>Liver Neoplasms (secondary)</term><term>Liver Neoplasms (therapy)</term><term>Stomach Neoplasms (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Humains (MeSH)</term><term>Tumeurs de l'estomac (anatomopathologie)</term><term>Tumeurs du foie (secondaire)</term><term>Tumeurs du foie (thérapie)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Tumeurs de l'estomac</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Stomach Neoplasms</term></keywords><keywords scheme="MESH" qualifier="secondaire" xml:lang="fr"><term>Tumeurs du foie</term></keywords><keywords scheme="MESH" qualifier="secondary" xml:lang="en"><term>Liver Neoplasms</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Liver Neoplasms</term></keywords><keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Tumeurs du foie</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Liver metastases of gastric carcinoma are often the synonym of advanced neoplastic disease which has long justified the indication of palliative chemotherapy. However, inspired by the good results of the management of liver metastases of colorectal cancers,several surgeons have focused on the treatment of liver metastases of gastric carcinoma. The different therapeutic modalities used are surgery, radiofrequency ablation, hepatic arterial infusion and palliative gastrectomy.</p></div><div type="abstract" xml:lang="en"><p><b>AIMS</b></p><p>To provide evidence based answer to the following questions regarding liver metastases from gastric carcinoma: 1. What is the indication of surgery? 2. Does radiofrequency ablation useful? 3. What is the contribution of the hepatic arterial infusion? 4. Is there any benefit to palliative gastrectomy?</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>A literature search on PubMed database over the period from January 1990 to December 2011 was conducted using as key words "gastric cancer" and "liver metastases".</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Surgery of a single liver metastasis smaller than 5 cm and not associated with another metastatic site offers better results in terms of 5-year survival rate than palliative chemotherapy. Intra hepatic arterial chemotherapy offers an alternative to surgery in inoperable patients and can be proposed as neo adjuvant treatment to surgery. The interest of radiofrequency ablation and palliative gastrectomy remains unproven.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Surgery is a good indication for single liver metastasis of gastric carcinoma less than 5 cm and not associated with another extra hepatic metastasis.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Bouasker, Ibtissem" sort="Bouasker, Ibtissem" uniqKey="Bouasker I" first="Ibtissem" last="Bouasker">Ibtissem Bouasker</name><name sortKey="Dziri, Chedly" sort="Dziri, Chedly" uniqKey="Dziri C" first="Chedly" last="Dziri">Chedly Dziri</name><name sortKey="Jerraya, Hichem" sort="Jerraya, Hichem" uniqKey="Jerraya H" first="Hichem" last="Jerraya">Hichem Jerraya</name><name sortKey="Khalfallah, Mehdi" sort="Khalfallah, Mehdi" uniqKey="Khalfallah M" first="Mehdi" last="Khalfallah">Mehdi Khalfallah</name><name sortKey="Nouira, Ramzi" sort="Nouira, Ramzi" uniqKey="Nouira R" first="Ramzi" last="Nouira">Ramzi Nouira</name><name sortKey="Saidani, Ahmed" sort="Saidani, Ahmed" uniqKey="Saidani A" first="Ahmed" last="Saidani">Ahmed Saidani</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/MaghrebDataLibMedV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000189 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000189 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= MaghrebDataLibMedV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:23404586
|texte= Management of liver metastases from gastric carcinoma: where is the evidence?
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23404586" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MaghrebDataLibMedV2
| This area was generated with Dilib version V0.6.38. |  |